What causes epididymal malformation?

Patient's question:

I don't have any bad habits, and I look quite healthy. I've been married to my wife for several years and have been trying to get pregnant, but for some reason, it just hasn't worked. Additionally, I have some cysts in my epididymis, but I don't have any other symptoms. The doctor said that infertility is caused by epididymal malformation. What causes epididymal malformation?

Doctor's answer:

Attached epididymal malformation may be related to endocrine dysfunction during embryonic growth and development. Due to excessively low testosterone levels, mesonephric tubules and mesonephric ducts fail to develop or develop incompletely, leading to various types of epididymal malformations, which can result in congenital absence of the epididymis and vas deferens. If growth and development terminate at a certain site, it can form a self-locking structure at that location. When the epididymal duct twists and coils around an obstacle, it can cause significant shortening of the epididymis. For patients with epididymal malformations, timely treatment can reduce the incidence of the condition.

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