What should be done if there is semen that does not liquefy?

Patient's question:

I have been married to my wife for many years, and we have never used any form of contraception, but we have never been able to conceive. After checking at the hospital, I found out that I have a problem with semen not liquefying. What should I do in this case?

Doctor's answer:

Treatment should first identify the cause. The common reasons for semen liquefaction failure include prostatitis and seminal vesiculitis leading to insufficient secretion of fibrinolysin by the prostate; deficiency of trace elements (such as magnesium, zinc, etc.); congenital absence of the prostate, and so on. It is generally believed that the secretions of the prostate and seminal vesicles contribute to the coagulation and liquefaction of semen. The coagulation factor produced by the seminal vesicle causes semen coagulation, while the liquefaction factors produced by the prostate, such as protein compressase and fibrinolysin, cause semen liquefaction. Once inflammation occurs again in the seminal vesicle or prostate, it may lead to the recurrence of impaired secretion of these factors, resulting in an increase in coagulation factors or liquefaction factors, which constitutes semen liquefaction failure. It is recommended to seek further diagnosis from a urology department to identify the cause and then receive targeted treatment.

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