What is the reason for BCG being negative?

Patient's question:

I received a shot of hepatitis B immune globulin in the 7th, 8th, and 9th months of pregnancy, and the baby got a shot of globulin at birth. However, I'm worried that the baby's hepatitis B vaccine may not have been successful either, and whether their antibodies are also negative. I'm very concerned that if the baby doesn't have antibodies, they might already be infected with hepatitis B? Because I have always been breastfeeding.

Doctor's answer:

Hello, a negative tuberculin skin test indicates that the child is not sensitive to the BCG vaccine, so it does not provide preventive effects. Therefore, a booster shot is needed. How are the results of your liver function and hepatitis B virus tests? If your baby's BCG vaccination fails, resulting in a negative test, it is important to provide a supplementary vaccination as soon as possible. Regarding your baby's hepatitis B immunity, the use of hepatitis B immune globulin is very effective. The best hepatitis B vaccine to administer is 10 micrograms, which would be even better. I believe you should still avoid breastfeeding, as chronic hepatitis B () is contagious.

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