What is the reason for high direct bilirubin in premature infants?

Patient's question:

Patient is male, 9 days old. Premature. Hospital examination shows high direct bilirubin, but the cause is unknown. What kind of help is desired: I want to know what impact it has on the child's health. How to treat it.

Doctor's answer:

This friend, your condition may be physiological jaundice. Neonatal jaundice refers to the increase in blood bilirubin levels caused by abnormal bilirubin metabolism during the neonatal period, leading to jaundice. This condition is divided into physiological and pathological types. Physiological jaundice appears 2 to 3 days after birth, peaks between 4 to 6 days, and disappears within 7 to 10 days. Premature infants have a longer duration, with only mild loss of appetite as the only clinical symptom. If jaundice appears within 24 hours after birth and does not subside within 2 to 3 weeks, or if it worsens after initially fading, or if it reappears after fading, or if it appears only after 1 to several weeks after birth, these are all signs of pathological jaundice.

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