Patient's question:
Once had a miscarriage in the first trimester, induced abortion in March this year (edema fetus)Doctor's answer:
If the couple is a different type of thalassemia patient (one α and one β), it has no impact on fertility. There is a 25% chance that the child will be completely normal, and a 75% chance that the child may have mild thalassemia. If the couple is the same type of thalassemia patient, chorionic villus sampling (CVS) or amniocentesis should be performed during pregnancy to check the fetal genotype, and decisions should be made based on the results. Generally, normal or mild thalassemia genotypes can be carried to term, with a probability of 75%. In other words, even if the parents are the same type of thalassemia, there is only a 1/4 (generally speaking) chance that they may need to consider termination. If both parents are carriers of 3.7 or 4.2α thalassemia deletion, although they are the same type of thalassemia, the child will still have no possibility of severe thalassemia. From the perspective of thalassemia, it is 100% viable to carry the pregnancy to term.