Genetic disease prenatal screening uE3 low, is it necessary to do prenatal again

Patient's question:

The prenatal check-up was done at 17 weeks. In the genetic disease prenatal screening, uE3 was 0.58, which is lower than the normal value of 0.71. All other tests were normal. The three screening items—Trisomy 21, Trisomy 18, and open neural tube defects—were also low risk.

Doctor's answer:

The best time to do a four-dimensional ultrasound is between the 5th and 8th months of pregnancy (20-28 weeks), because during this period, the limbs and major organs of the fetus have fully developed, and the amniotic fluid is more suitable for fetal anomaly screening. However, due to individual differences among pregnant women, please contact your doctor to determine the specific time according to medical advice.

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