Patient's question:
Expert, hello. I am 28 years old this year, married for more than 2 years, and have not had children yet. Our family often faces crises, which troubles me greatly. Later, after checking at the hospital, I was diagnosed with endometriosis, which has been more than a year. The expert suggested using conservative treatment, so I would like to consult about which treatment method is the best for endometriosis. I hope someone can help me answer this.Doctor's answer:
Danaazol: It is a derivative of synthetic 17α-ethynyl testosterone. Its main function is to inhibit the production of GnRH in the hypothalamus, thereby reducing the synthesis and release of FSH and LH, leading to the suppression of ovarian function. It can also directly inhibit the synthesis of ovarian steroid hormones or compete with estrogen and progesterone receptors, resulting in atrophic changes in ectopic endometrium, anovulation, and amenorrhea. Danaazol also has mild androgenic effects, producing masculinization symptoms such as increased hair growth, a lower voice, reduced breast size, and acne. Another common side effect of danaazol is fluid retention and weight gain. It is not recommended for use in individuals with hypertension, heart disease, or impaired renal function. Danaazol is primarily metabolized by the liver and may cause certain damage to liver cells, so women with liver diseases are contraindicated for its use.