What should be done about neonatal hemolytic disease caused by incompatible AB0 blood type?

Patient's question:

A friend of mine has recently reached the late stage of pregnancy. My friend is type O blood. I've heard that this situation can easily lead to blood type incompatibility. I would like to consult about whether ABO blood type incompatibility can cause hemolysis in the child.

Doctor's answer:

Hemolytic disease of ABO blood type incompatibility between mother and fetus is a type of neonatal hemolytic disease. It is called "neonatal ABO hemolytic disease." It is an autoimmune hemolytic disease of the same origin. Most neonatal hemolytic diseases in China are ABO hemolytic diseases. During pregnancy or delivery, a large number of fetal red blood cells may enter the mother's body. If their blood types do not match, the mother lacks fetal red blood cell antigens. The mother will then produce corresponding antibodies. Currently, if the mother is type O blood and the next generation is not type O blood, the incidence rate is relatively high.

📌 Related Posts