Didn't have the Down syndrome screening, is it necessary to have an amniocentesis?

Patient's question:

Pregnant 29 weeks, weight 61 kg, good appetite, poor sleep, baby's movements are frequent, frequent urination, often hungry at night. Ultrasound is normal, just a bit anemic.

Doctor's answer:

Analysis of the condition: It is not possible to skip the Down syndrome screening in this case. Generally, amniocentesis is performed after Down syndrome screening.
Advice: Additionally, Down syndrome screening is not related to whether medications or alcohol were consumed during pregnancy. It is primarily used to assess the risk of trisomy 21.

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