What are the causes of female immunological infertility?

Patient's question:

Hello! We have been married for 2 years and still haven't had any children. When we went to the hospital for a check-up, there were no reproductive organ diseases found. One doctor suspected that it might be due to an immunological reason. Could you please ask the experts what are the causes of immunological infertility?

Doctor's answer:

Hello! Immunological infertility is a very special type of infertility, and in most cases, people only check if it is caused by immunological factors when they are unaware of the cause of their infertility. The main reasons are as follows:
1. The presence of antisperm antibodies in a woman's body, which have cytotoxic effects on sperm.
2. The presence of antibodies in the body promotes the phagocytic function of phagocytes, leading to the clearance of sperm from the reproductive tract.
3. Local antibodies in the body cross-react with components of oocytes, inhibiting cell development.
4. Some local antibodies in a woman's body can interfere with the energy of sperm in the reproductive tract.

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