Patient's question:
Breasts have become noticeably larger than before, without pain or discomfort. I would like to ask for your advice and see if the problem is serious?? Patient gender: Patient age:Doctor's answer:
The occurrence of the disease is mainly due to an absolute or relative increase in estrogen levels in the body, or an increased sensitivity of breast tissue to it. Both men and women secrete both androgens and estrogens in their bodies, but the difference in proportion reflects gender differences. Therefore, any factor that leads to high estrogen levels or reduced androgen secretion can trigger this condition. For example:1. Diseases of the adrenal cortex—the primary site of estrogen secretion—can cause abnormally elevated estrogen levels.
2. If the liver, the main site of estrogen metabolism, becomes diseased and liver function declines, estrogen accumulates excessively in the body, leading to the condition.
3. The testes are the primary organ for androgen secretion. Disorders such as testicular tumors or congenital testicular hypoplasia can reduce androgen production, resulting in relatively higher estrogen levels and triggering the condition.
4. Other diseases, such as hypothalamic-pituitary disorders, thyroid disease, diabetes, sexual differentiation abnormalities, and chronic colitis, can also cause this condition. Certain medications, such as progesterone, isoniazid, tricyclic antidepressants, and digitalis, can affect estrogen metabolism and induce breast enlargement.