Patient's question:
I am 27 years old this year. I have had two medication-induced miscarriages in the past, both around 40 days, with the last one occurring in September 2004. Last year, we decided to have a child, but in late October (when I was almost three months pregnant), I miscarried. The examination revealed that the fetus was not developing. My last menstrual period was on January 26th of this year, and in early April, I experienced another missed miscarriage.Doctor's answer:
It is best to identify and treat the underlying cause of habitual miscarriage before pregnancy, otherwise the same mistake may be repeated. If there is a history of fetal demise and spontaneous abortion, it is advisable to identify the cause before pregnancy. On days 3-5 of the menstrual cycle, endocrine tests and anti-embryonic antibody tests should be conducted using electrochemical luminescence method. On days 3-5 after the menstrual period ends, vaginal colposcopy, dynamic digital hysterosalpingography, and vaginal four-dimensional color Doppler ultrasound should be performed. Generally, this can lead to a definitive diagnosis, and some patients may require further examination with electronic hysteroscopy or laparoscopy.If already pregnant, an ultrasound should first be done to confirm the condition of the embryo. Anti-embryonic antibody tests, progesterone, and HCG should be conducted using electrochemical luminescence method. If fetal demise has occurred, hysteroscopic embryo removal should be performed, along with testing for embryonic chromosome abnormalities and uterine cavity environment.
Not all miscarriages are caused by anti-embryonic antibodies—less than 0.1% of cases are, and it only occurs under specific conditions.