Patient's question:
The first child has albinism, and now they want a second one but don't know how to avoid it.Doctor's answer:
Albinism is a relatively common disease caused by the lack of melanin in the skin and its appendages, resulting from a congenital deficiency of tyrosinase or a decline in tyrosinase function, which hinders melanin synthesis and leads to hereditary leukoplakia.Medical Advice:
Albinism is generally inherited in an autosomal recessive manner, often caused by consanguineous marriage. This means both parents carry the albinism gene but do not exhibit symptoms themselves. If both parents pass on the disease-causing gene to their offspring, the child will be affected, with an equal chance of the child being male or female. The probability of this occurring is 1/4. Genetic diagnosis is currently the most reliable method for differential diagnosis and prenatal diagnosis.