Patient's question:
How have I had three natural miscarriages in these three years. The check revealed immune infertility, and each time it was over forty days before it was lost.Doctor's answer:
1. Polycystic Ovary Syndrome: Approximately 40% of patients with Polycystic Ovary Syndrome experience recurrent spontaneous abortion, mainly due to conditions such as hyperprolactinemia, luteal phase defect, low estrogen levels, poor oocyte quality, and endometrial abnormalities.2. Luteal Phase Defect: The ovarian corpus luteum secretes progesterone. A deficiency in progesterone can lead to inadequate endometrial development, hindering implantation of the zygote and early embryonic development. Before the 8th week of pregnancy, the primary source of progesterone is the corpus luteum of pregnancy. After the 8th week, the placental trophoblast gradually replaces the corpus luteum as the main source of progesterone. If progesterone is insufficient before the 8th week, it may result in miscarriage.