What factors or causes can lead to habitual abortion?

Patient's question:

Multiple miscarriages occurred, but all hormone tests and other checks were normal. What factors or causes could lead to habitual abortion?

Doctor's answer:

1. Genetic factors: If either partner or both partners have chromosomal abnormalities, it can lead to the inability of the embryo to survive, which in turn can cause habitual abortion. Therefore, it is recommended that both partners undergo detailed examinations before pregnancy.
2. Luteal phase defect: If a woman has a luteal phase defect after conception, it can result in insufficient secretion of progesterone and estrogen, which can affect the development of the zygote and ultimately lead to abortion.
3. Uterine developmental abnormalities: If a woman has uterine malformations, such as bicornuate uterus, uterine hypoplasia, or conditions like intrauterine adhesions or uterine fibroids, it can also make habitual abortion more likely.

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