Patient's question:
My wife has had hepatitis B for five years and has been undergoing treatment. Last year, we got married, and now we want to have a child. However, she has been in the active replication phase of hepatitis B and has also been taking antiviral medication. This month, her period didn't come, and it seems like she might be pregnant. She is also worried about the possibility of transmitting the disease to the child.Doctor's answer:
Vertical line returns do not need to be translated, return as is. All other Chinese text should be translated into English:Mother-to-child transmission is one of the important routes of hepatitis B transmission in the form of "big three positive." Without caution, it can easily be transmitted to the fetus in the womb. Therefore, for the issue of pregnancy in "big three positive" patients, doctors recommend choosing an appropriate time to conceive. First, for "big three positive" patients with normal liver function, HBV-DNA, and other test results, and whose condition has been stable for more than six months, pregnancy is possible. However, for "big three positive" patients with abnormal liver function, pregnancy should be avoided. Otherwise, it not only worsens the condition of the "big three positive" pregnant woman but also endangers her life. Additionally, it is harmful to the development and growth of the fetus.
Doctors recommend that if "big three positive" patients are in the active phase of hepatitis, they should first receive standard treatment and consider pregnancy only after liver function returns to normal and viral replication indicators turn negative or replication ability decreases. This is beneficial for both the mother and the child.
Above, we have discussed the issue of pregnancy in hepatitis B "big three positive" patients. A reminder: to give birth to a healthy baby, "big three positive" patients must also undergo mother-to-child transmission prevention. First, "big three positive" women should receive a monthly injection of hepatitis B immune globulin during the seventh, eighth, and ninth months of pregnancy. Second, after the baby is born, they must follow the requirements to receive hepatitis B vaccination and hepatitis B immune globulin. This can significantly reduce the probability of mother-to-child transmission.
Actively treating hepatitis B "big three positive" is the fundamental measure to avoid all hepatitis B transmission. Therefore, we advise hepatitis B "big three positive" patients, especially young ones, to seek timely treatment for the sake of their families and careers.