Patient's question:
Endocrine diseases are something that every woman has to some extent. Yesterday, I went to Yunnan Ren Ai Hospital for a check-up, and they said I have an endocrine disease. I don't know if this condition is very serious.Doctor's answer:
A syndrome that occurs when there are abnormalities in the secretory function and/or structure of endocrine glands or endocrine tissues. It also includes syndromes caused by abnormal hormone sources, abnormal hormone receptors, and physiological disorders resulting from abnormal hormone or substance metabolism.Guidelines for the treatment of hyperfunction include:
1. Surgical removal of tumors or hyperplastic tissues causing hyperfunction;
2. Radiotherapy to suppress secretory function;
3. Drug therapy to inhibit hormone synthesis and release or block their action on receptors, such as thioamides inhibiting thyroid hormone synthesis and spironolactone antagonizing aldosterone's action on renal tubular epithelial cell receptors;
4. Using target gland hormones to suppress the synthesis and secretion of trophic hormones, such as corticosteroids inhibiting ACTH to reduce excessive androgen production by the adrenal cortex in congenital adrenal hyperplasia;
5. Chemotherapy, such as using o,p′-DDD (1,2-dichloro-4-(o-chlorophenyl)benzene) or aminoglutethimide to treat adrenal cortex cancer;
6. Using certain drugs to regulate hypothalamic-pituitary-target gland axis dysfunction caused by neurotransmitters, such as bromocriptine treating prolactinomas or hyperprolactinemia.
For hypofunction, replacement therapy is generally adopted to supplement the physiological demand for hormones. For example, hypothyroidism is treated with thyroid tablets, and adrenal insufficiency is treated with cortisol or prednisone, while symptomatic and supportive therapy should also be provided. If the underlying cause is clear, the cause should be eradicated, such as administering antitubercular treatment for adrenal tuberculosis.