Can follicular maturation disorders be treated?

Patient's question:

The oocytes retrieved from the test tube were immature, but the ultrasound showed that the follicles were 18-20.5 in size. There were a total of 17 follicles, all of which were immature.

Doctor's answer:

Patients with follicles but no ovulation often suffer from endocrine disorders such as polycystic ovary syndrome, hyperprolactinemia, and hyperandrogenemia. Ovulation requires the formation of an LH peak. If the hypothalamic-pituitary-ovarian axis regulation is disrupted, the formation of a low LH peak, i.e., insufficient LH secretion, will affect ovulation.

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