Treatment methods for intrahepatic cholestasis of pregnancy

Patient's question:

Patient gender: Female
Laboratory test results:

Doctor's answer:

Cholestasis of the intrahepatic bile ducts (ICP) is a specific complication of pregnancy in the second and third trimesters, clinically characterized by symptoms such as skin itching and jaundice, as well as insomnia, fatigue, nausea, vomiting, and reduced appetite. It poses risks to the fetus, increasing perinatal morbidity and mortality.
After clinical diagnosis of ICP, appropriate bed rest, lateral positioning, increased placental blood flow, oxygen supplementation, vitamin supplements, and energy support can improve fetal tolerance to hypoxia. Regular liver function and blood bile acid tests are recommended.
Medications include ursodeoxycholic acid to reduce bile acid levels, improve fetal environment, alleviate itching, and enhance biochemical indicators. Other options include S-adenosylmethionine and phenobarbital-induced liver enzymes.
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