Patient's question:
Hello, I have been married for seven years and have not been able to conceive a child. The hospital check-up showed positive anti-sperm antibodies, and I have taken many medications without any effect. Additionally, my husband's sperm quality is a bit weak. Could you please advise on any methods that could help me conceive a child? Thank you.Doctor's answer:
Hello: Antisperm antibodies are a complex pathological product, affecting both men and women, with their exact factors or etiology not yet fully understood. The sperm and seminal fluid of men are specific antigens for women. Upon contact with blood, they can cause immune reactions in both men and women, leading to the production of corresponding antibodies that hinder sperm from fertilizing eggs, resulting in infertility. These conditions are classified as immunological infertility. Female patients with positive antisperm antibodies often have a history of reproductive system infections such as endometritis, vaginitis, and tubulitis before the onset of their condition, which is particularly common in cases of tubal obstruction infertility. These patients frequently have a history of sexual intercourse during menstruation, postpartum lochia retention, or abnormal vaginal bleeding. Even if they have the opportunity to conceive, the fertilized egg may be affected by the disease or weakened, making it highly susceptible to atrophy or death during the embryonic stage, leading to spontaneous abortion. For immunological infertility, isolation therapy and immunosuppressive therapy are recommended. It is advised to seek treatment at a reputable and authoritative specialized hospital as early as possible to avoid missing the optimal age for conception. Wishing you good health!