Patient's question:
I've been married for 5 years, and we've never had children. At first, we thought it was due to my wife's factors or medical conditions. A few days ago, my wife and I went to the hospital for check-ups. The results showed that I have immunological infertility. It's because I had an injury and infection in my testicles when I was a child, but it later healed. I don't know if this is related to the factors or conditions causing the issue.Doctor's answer:
Causes or factors of immunological infertility: Cause 1: Antigens and antibodies in semen.Causes or factors of immunological infertility: Cause 2: Autoimmune response to sperm.
Causes or factors of immunological infertility: Cause 3: Research on the reproductive immune system has confirmed the presence of a blood-testis barrier between the blood and the testes. Antigens in sperm are digested, and the antigenic information is transmitted to lymphocytes, leading to humoral or cellular immune responses. This results in the destruction of tissues such as the testes, epididymis, and vas deferens, causing autoimmune orchitis and leading to infertility.