Patient's question:
What factors or causes lead to the atrophy of the corpus luteum? What effects does it have on the body?Doctor's answer:
Luteal phase defect refers to insufficient progesterone secretion by the corpus luteum or premature luteal regression, leading to poor secretion of the endometrium and consequently difficulty in implantation of the fertilized egg or early pregnancy miscarriage. Luteal phase defect may be related to insufficient secretion of LH and FSH by the pituitary gland or excessive/prolonged prolactin secretion by the pituitary gland. In some cases, it may be due to the immaturity of the fertilized egg itself, making it unresponsive to gonadotropins. In other cases, it may be related to insufficient ability of the corpus luteum to synthesize progesterone or an imbalance in the ratio of estrogen and progesterone.Recommendation: Luteal phase defect can easily lead to miscarriage or infertility, so it is recommended that you seek a detailed examination at a specialized hospital as soon as possible for symptomatic treatment.