Patient's question:
My younger brother is getting married next month, but apart from happiness, he is more worried. A few years ago, because his penis was smaller than others and his testicles on both sides were very small, appearing to be around 2 cm in size with a hard texture, he went to the hospital for a check-up. The doctor then said he had congenital hypoplasia of the testes. He underwent treatment, but it had no effect.Doctor's answer:
Hello, the formation of Klinefelter syndrome may be due to the failure of sex chromosomes to separate during the maturation division of oocytes, resulting in an oocyte containing two X chromosomes. If this oocyte combines with a Y sperm, it forms a 47, XXY fertilized egg. If a germ cell fails to separate XY during the first maturation division, it forms an XY sperm. This sperm can also combine with an X egg to form a 47, XXY fertilized egg. It is generally believed that most 47, XXY formations are caused by the failure of sex chromosomes to separate during the maturation division of oocytes.