Which diseases are prone to cause female infertility

Patient's question:

Which diseases are prone to cause female infertility

Doctor's answer:

Which diseases are prone to cause female infertility? In response to many female patients recently asking me "Which diseases are prone to cause female infertility?", we have specially invited a gynecological expert from Nanjing Mary Hospital to explain this for everyone. There are many diseases that can cause female infertility. According to analysis, most patients suffer from infertility due to endocrine disorders or gynecological inflammation that has not been treated in time. The main diseases that are prone to cause female infertility include:
Infertility caused by cervical diseases: The cervix is the first passageway for sperm to pass through. Any anatomical or physiological changes in the cervix can affect sperm passage and lead to infertility. Clinical manifestations mainly include cervical canal atresia and stenosis, cervical canal developmental abnormalities, abnormal cervical position, cervical fibroids, chronic cervical inflammation, and abnormal cervical mucus, etc.
Infertility caused by external genitalia and vaginal disorders: Diseases affecting the external genitalia and vagina, either structurally or functionally, can impact semen or sperm entry. Clinical manifestations include hermaphroditism, hymen atresia, transverse vaginal septum, congenital absence of the vagina, vaginal stenosis and adhesions, etc.
Infertility caused by uterine disorders: Uterine malformations, developmental abnormalities, endometritis, uterine fibroids, intrauterine adhesions, abnormal uterine position, and endometrial dysfunction can all affect sperm movement, fertilization egg implantation, and fetal development and growth, leading to infertility or miscarriage.
Infertility caused by endometriosis: The factors or causes are relatively complex. Adhesions caused by pelvic and abdominal endometrial lesions can lead to fallopian tube dysfunction and blockage of the fallopian tube lumen; ovarian lesions can affect normal ovulation.
Ovarian infertility: Ovarian developmental abnormalities, dysfunction, or tumors can all affect human development, health, and fertility. Reproductive gland developmental abnormalities, true hermaphroditism, testicular feminization syndrome, XXX syndrome, ovarian inflammation, and ovarian tumors are all clinical factors or causes leading to ovarian infertility.
Infertility caused by endocrine disorders: Clinical manifestations include ovulation disorders, amenorrhea, polycystic ovary syndrome, etc.
Infertility caused by fallopian tube disorders: Factors or causes leading to fallopian tube blockage or dysfunction include acute and chronic fallopian tube inflammation, adhesions, and blockages.
Immune infertility: Accounts for approximately 10% to 30% of infertile patients. Clinical manifestations mainly include antisperm immune infertility and immunological infertility against the zona pellucida.
Infertility caused by habitual abortion: Repeated natural abortions three or more times are referred to as habitual abortion.
Infertility after artificial abortion: Artificial abortion can easily cause endometrial damage and uterine adhesions, affecting fertilization egg implantation and leading to infertility; it can also cause fallopian tube adhesions, leading to infertility; it can trigger endometriosis, causing infertility; and endocrine dysfunction such as luteal insufficiency, anovulation, and galactorrhea can also lead to infertility.
Currently, about 80% of infertility factors or causes can be diagnosed clearly through various advanced equipment, and 70% of infertility cases can be preliminarily resolved. Experts from Nanjing Mary Infertility and Sterility Department point out that diagnosis is very important for treating infertility, especially for the first consultation. If it is not handled properly at the beginning, it may cause difficulties for subsequent treatment.

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