Patient's question:
What factors or causes can lead to endometrial thickening?Doctor's answer:
Endometrial hyperplasia is caused by excessive estrogen stimulation of the endometrium. Clinically, it manifests as irregular, excessive abnormal uterine bleeding. Patients may experience persistent bleeding after a long period of amenorrhea. It can also be suspected as a miscarriage, or it may present as a shortened cycle, prolonged menstruation, with bleeding duration reaching up to one month. Pathological examination shows that the degree of endometrial hyperplasia does not always correlate with the severity of bleeding. It is characterized by endometrial thickening, with thickness varying from 3 to 12 millimeters, and in some cases, it can even reach 20 millimeters. The endometrium appears grayish-white or pale yellow, with a smooth surface or polypoid elevations, and may be accompanied by edema. The cut surface sometimes reveals dilated glands forming cystic spaces. It is recommended to actively undergo a six-panel sex hormone test. The clinical significance of the six-panel sex hormone test is to understand female endocrine function and diagnose endocrine-related diseases by measuring sex hormone levels. The commonly used six-panel sex hormones include Follicle-Stimulating Hormone (FSH), Luteinizing Hormone (LH), Estradiol (E2), Progesterone (P), Testosterone (T), and Prolactin (PRL), which generally meet the clinical needs of doctors for screening endocrine disorders and assessing physiological functions. If blood is drawn on an empty stomach on the third day of the menstrual period, it can be tested at any time if the menstrual period is prolonged, but reference values may differ.