Patient's question:
Hello, how can sperm antibodies in the body disappear quickly?Doctor's answer:
With the development of medical science and the continuous improvement of detection methods, immunological infertility has been gaining increasing attention. Immunological infertility refers to infertility caused by autoimmune or allogenic immune responses to antigens in the reproductive system. Sperm, seminal plasma, the zona pellucida of the egg, and steroid hormone-producing cells within the ovaries are all specific antigens that can trigger immune responses, leading to the production of corresponding antibodies. These antibodies hinder the combination of sperm and eggs, resulting in infertility. Among these causes, infertility caused by antisperm antibodies is the most common.Sperm, as a unique antigen, can elicit autoimmune or allogenic immune responses upon contact with the body's immune system, producing antisperm antibodies.
Recommendations: For the treatment of antisperm antibodies, Western medicine currently employs methods such as using prednisone and other adrenal cortical hormones to suppress immune responses. Another approach involves using washed sperm for artificial insemination in men. For patients with positive antisperm antibodies, it is recommended to consistently use condoms during intercourse for 3 to 6 months to avoid contact between the female reproductive tract and sperm. After the titer of antisperm antibodies in the body decreases or disappears, the use of condoms can be discontinued, which may then lead to pregnancy.