What are the effects of antisperm antibodies on pregnancy?..

Patient's question:

What are the effects of antisperm antibodies on pregnancy? What are the effects of anti-endometrial antibodies on pregnancy? What are the effects of anti-hCG antibodies on pregnancy? I hope it's detailed, thank you.

Doctor's answer:

Hello: Antisperm antibodies are a complex pathological product, affecting both men and women, with their exact factors or etiology not yet fully understood. The sperm and seminal plasma of men are considered specific antigens for women. Upon contact with the bloodstream, they can trigger immune reactions in both men and women, leading to the production of corresponding antibodies that hinder the combination of sperm and eggs, resulting in infertility. The aforementioned conditions fall under the category of immunological infertility. Female patients with positive antisperm antibodies often have a history of reproductive system inflammation such as endometritis, vaginitis, or tubulitis before the onset of their condition, which is particularly common in cases of infertility due to tubal obstruction. For immunological infertility, isolation therapy and immunosuppressive therapy are recommended. We advise you to visit our hospital for early treatment and not to miss the best age for conception. Wishing you health!

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