Patient's question:
Accidentally ejaculated inside my wife during sex, and I thought we might be pregnant. But she wasn't pregnant. I wondered if we couldn't get pregnant, so I took her to the hospital for a check-up. The result showed that my wife's antisperm antibody was positive. What does this mean?Doctor's answer:
Positive for antisperm antibodies. The presence of antisperm antibodies can prevent sperm and eggs from combining to form a fertilized egg or affect the implantation of the fertilized egg, thereby impacting fertility. The systemic treatment for antisperm antibodies involves using corticosteroids like prednisone to suppress the immune response. Additionally, for men, sperm can be washed in a culture medium before artificial insemination. For women, it is recommended to use condoms for 3-6 months to avoid contact between the female reproductive tract and sperm, allowing the titer of antisperm antibodies in the body to decrease or disappear before stopping condom use and engaging in sexual intercourse, which may then lead to pregnancy. By removing the stimulation of sperm antigens, the titer of antisperm antibodies will decrease. Testosterone therapy works on this principle. High doses of testosterone can inhibit sperm production, causing azoospermia. Without the stimulation of sperm antigens, the titer of antisperm antibodies may decrease or normalize. After treatment is stopped, sperm and antisperm antibodies return to pre-treatment levels, but some patients may remain free of antisperm antibodies for a period and achieve pregnancy. It is available over-the-counter, but it often has significant side effects. You can visit a large, reputable hospital for comprehensive testing.