Irregular menstruation and infertility are they signs of Polycystic Ovary Syndrome?

Patient's question:

In January 2014, my menstrual cycle was abnormal. It remained irregular for over a year, and then for two years. In July 2014, I went to West China Hospital for a check-up and was diagnosed with polycystic ovary syndrome. I took three boxes of Yasmin, and it became normal. However, it returned to being abnormal afterward.

Doctor's answer:

Increase exercise to reduce weight, correct endocrine and metabolic disorders exacerbated by obesity, reduce insulin resistance and hyperinsulinemia, lower IGF-1, increase IGfBP-1, and simultaneously increase SHBG to reduce free androgen levels. Weight loss can restore ovulation in some obese women with PCOS and prevent the occurrence of type 2 diabetes and cardiovascular diseases. Metformin treatment can be used for both diabetic and non-diabetic individuals, effectively reducing weight, improving insulin sensitivity, lowering insulin levels, reducing hair growth, and even restoring menstruation (25%) and ovulation. Since obesity and insulin resistance are the main causes of PCOS, any drug that can reduce weight and increase insulin sensitivity can treat this syndrome.

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