What are the causes of obstructive azoospermia?

Patient's question:

What are the causes of obstructive azoospermia? After examination, my husband was found to have obstructive azoospermia. What are the general factors that cause obstructive azoospermia?

Doctor's answer:

The occurrence of obstructive azoospermia is related to the following factors:
1. Inability to produce sperm due to testicular inflammation, often caused by mumps, but other infections can also lead to this condition.
2. Ingestion of cottonseed oil can cause testicular atrophy and damage to reproductive cells, resulting in the production of dead sperm.
3. Severe varicocele can lead to poor blood circulation in the testicles, elevated local temperature, and an unfavorable environment for sperm production, causing azoospermia.
4. Sertoli cell syndrome is caused by congenital or acquired factors that result in the loss of germ cells, leaving only Sertoli cells and leading to azoospermia.
5. Obstruction in the pathway of sperm passage can cause the semen to be emitted without sperm, such as when gonorrhea sometimes blocks the vas deferens.

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