What causes semen to not liquefy

Patient's question:

Hello doctor, I would like to consult about the causes of semen not liquefying? I was told that I have semen liquefaction disorder, but I haven't felt any discomfort. It just so happens that I'm trying to have a child right now, which is really unlucky. What are the causes of semen not liquefying?? Will it affect fertility?

Doctor's answer:

Ejaculate does not liquefy due to a lack of secretion or damage of proteolytic enzymes, leading to an imbalance in the enzyme system. This results in some patients' semen remaining unliquefied even after being placed for 1 hour, or liquefying incompletely with excessively high viscosity. In such cases, sperm cannot move forward, naturally causing infertility. This condition is associated with infections in accessory glands that impair the secretion of proteolytic enzymes, fibrinolytic enzymes, and seminal liquefaction factors, preventing the liquefaction of semen. It is recommended that you visit a specialized hospital for a detailed examination to identify the underlying cause and receive targeted treatment.

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