If the non-invasive DNA test result is high risk, is it still necessary to have an amniocentesis?

Patient's question:

Previously, during the Down syndrome screening, it was detected as Trisomy 21, and then the non-invasive DNA test still showed high risk! Is it still necessary to undergo amniocentesis? Can the child still be kept in this situation?

Doctor's answer:

Tang screen test, which is the abbreviation for prenatal screening for Down syndrome. The purpose is to determine the risk level of the fetus suffering from Down syndrome by testing the pregnant woman's blood. If the results of the Tang screen test show a high risk of the fetus having Down syndrome, further diagnostic tests such as amniocentesis or chorionic villus sampling should be conducted. After confirmation, the family can decide whether to keep the baby based on their circumstances. If it is the first child, it is recommended to be cautious, as high-risk miscarriage can easily lead to infertility.

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