How to treat polycystic ovary syndrome in a 13-year-old?

Patient's question:

Doctor:
　　Hello!
My daughter is 13 years old this year, and she started her menstrual period this year. The third time, it took more than a month to clean up. I took her to see a doctor, who diagnosed her with polycystic ovary syndrome. Is there such a small medical record? How long will it take to treat? Will it affect her in the future? The doctor has prescribed megestrol acetate tablets and ethinyl estradiol tablets. Will this affect the child's development?

Doctor's answer:

Hello: There are such cases
The main goal of polycystic ovary syndrome (PCOS) treatment is to establish a normal ovulatory menstrual cycle, restore fertility, and eliminate hirsutism. Once a normal menstrual cycle is established, pregnancy can occur, the ovaries no longer produce excessive androgens, and hirsutism also disappears. The methods to restore a normal menstrual cycle are as follows.
(1) Clomiphene, also known as clomiphene citrate or Serophene. It is now widely recognized that clomiphene is the first-line treatment for PCOS. Clomiphene induces the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus, which in turn promotes the release of follicle-stimulating hormone (FSH) from the pituitary gland, thereby promoting normal follicular development. Elevated FSH levels are key to inducing ovulation in PCOS patients. Clomiphene treatment can induce ovulation in more than 80% of patients. The specific dosage is 50 mg once daily, starting from day 5 of the menstrual cycle, for 5 consecutive days. Ovulation typically occurs 7–10 days after starting the medication. If treatment for 1–2 cycles is ineffective, the dose can be increased to 100 mg daily for 5 days. During treatment, basal body temperature is measured to observe for the presence of an ovulatory biphasic pattern.
(2) Ovarian wedge resection, which involves the removal of a wedge-shaped portion of the ovary. Before the introduction of clomiphene, the treatment for PCOS was ovarian wedge resection. The efficacy was significant. Most patients ovulated and became pregnant shortly after surgery. With the availability of clomiphene, ovarian wedge resection is rarely used today and is reserved only for patients who do not respond to medication.
(3) Traditional Chinese Medicine. The method of invigorating blood and tonifying the kidneys to induce ovulation has shown good results.