What is the reason for bleeding during the use of Chibujiale?

Patient's question:

Medical Description: Female patient, 29 years old, primary infertility. Current Condition: Bleeding on the 15th day of taking Fertilemax. Treatment History and Effect: Have taken it before, but this situation has not occurred. Ultrasound shows endometrial thickness of 7.5mm, no dominant follicle observed. Desired Help: I would like to ask the doctor if I should stop taking Fertilemax now. Also, is this bleeding considered a menstrual period?

Doctor's answer:

Hello; Premarin is an estrogen that is usually taken with progesterone to regulate the menstrual cycle, becoming a artificial cycle therapy. During the course of taking Premarin, breakthrough bleeding may occur, which is typically light spotting and does not affect medication. This artificial cycle therapy cannot be missed and should not be stopped arbitrarily. It can only be discontinued after completing a full menstrual cycle. Stopping medication arbitrarily may lead to more irregular vaginal bleeding. It is recommended to continue taking the medication. Generally, the bleeding during this period is relatively light. After completing a cycle, the bleeding may increase, which is then considered withdrawal bleeding post-medication, or what is commonly referred to as the menstrual period in an artificial cycle.

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