Patient's question:
After fourteen days of embryo transfer in IVF, if pregnancy hasn't occurred, does it mean it hasn't implanted?Doctor's answer:
There are test tubes where the embryo is implanted into your uterus after it survives to allow it to implant on its own, so there can be implantation issues. Those that don't react are even smaller than rice grains—none react when placed in your hand, and even less so inside the uterus. After the eggs are retrieved, they are incubated with sperm in the test tube. Each egg requires about 100,000 sperm to fertilize. After fertilization, the zygote divides to form early-stage embryos, consisting of 2 to 8 blastomeres, when it can be transferred for embryo transfer (ET). This typically occurs about 48 hours after egg retrieval, though this timing can be adjusted slightly depending on the specific situation, such as delaying it by one day, which may be more favorable for selecting the optimal embryo. If it's too early, the uterine environment may not be conducive to accepting the embryo. Generally, a trial transfer is performed in the outpatient clinic in the cycle before the stimulation cycle to determine the position of the uterus, the angle between the cervix and the uterine body, and the length of the uterine cavity, along with slight dilation of the cervix. After disinfecting the external genitalia, the speculum is used to expose the vaginal canal during the transfer.