Can a blood test detect if a child has Down syndrome at five months of pregnancy?

Patient's question:

Maternal and Child Health Station, had blood tested, the doctor said it might be mental retardation, I want to ask, can a urine test detect if the child is mentally retarded? What kind of assistance is needed: get answers, are there such cases, can a urine test detect how mentally retarded the fetus is?

Doctor's answer:

It should be a Down syndrome screening. It is a test method that extracts pregnant women's serum, examines the concentration of alpha-fetoprotein and human chorionic gonadotropin in maternal serum, and combines the pregnant woman's due date, age, weight, and gestational age at the time of blood collection to estimate the risk coefficient of giving birth to a child with Down syndrome.
Guidance: The best time to perform the screening is between the 15th and 20th weeks of pregnancy. Generally, pregnant women can receive the screening results within one week of blood collection. If the result is high-risk, there is no need to panic, as further tests such as amniocentesis and fetal chromosome examination are required to confirm the diagnosis.

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