Patient's question:
The prenatal check-up was done at 17 weeks. In the genetic disease prenatal screening, uE3 was 0.58, which is lower than the normal value of 0.71. All other results were normal. The three screening items—Trisomy 21, Trisomy 18, and open neural tube defects—were also low risk.Doctor's answer:
uE3 is the main estrogen produced by the fetal placental unit, and its level in maternal serum increases with gestational age. Mothers carrying a fetus with Down syndrome exhibit lower uE3 levels in their blood, with an average MOM value of 0.7. It is recommended to undergo an amniocentesis to clarify the situation. I hope this is helpful to you.Generally, doctors advise women with risk signs during prenatal examinations to maintain good personal hygiene and avoid sexual activity. Additionally, patients should create an environment conducive to emotional stability and stress relief. Wishing the patient a healthy delivery.