Fetal skin edema and thickening, bilateral pleural effusion - what causes it?

Patient's question:

Pregnancy at 7 months, fetal generalized skin edema and thickening. Bilateral pleural cavities filled with fluid shadows, compressing both lungs to the hilar region, with unclear outlines. Maximum amniotic fluid thickness is 137 mm.
Ultrasound diagnosis:
1. Single fetus, late pregnancy
2. Bilateral pleural effusion and edema in the fetus
3. Polyhydramnios
Maternal blood type:
ABO forward typing: B
ABO reverse typing: B
RH (D) blood type: Positive
Paternal blood type:
ABO: AB
RH (D): Positive
Maternal blood biochemistry:
Alanine aminotransferase (ALT): 4.0
Sodium (Na): 130.8
Carbon dioxide binding capacity (CO2-CP): 18.0
Urea nitrogen (BUN): 2.7
Creatinine (Crea): 47.8
Uric acid (UA): 354
Triglycerides (TG): 1.99
Apolipoprotein A1 (ApoA1): 1.67
Serum albumin (ALB): 36.1
Globulin (GLO): 24.4
Albumin/Globulin ratio (A/G): 1.48
Cholinesterase (CHE): 4075

Doctor's answer:

The causes of fetal hydrops are many, including infections, severe infectious diseases in the mother, chromosomal abnormalities, etc. In your current situation, the child's survival rate is already very low, so it is not advisable to continue carrying the pregnancy. Therefore, you can follow your doctor's advice and consider undergoing comprehensive preconception genetic testing before the next pregnancy. Generally, doctors recommend that patients with risk signs of prenatal examinations maintain good personal hygiene and avoid sexual activity. Additionally, patients should create an environment conducive to emotional stability and stress relief. Wishing the patient a healthy delivery.

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