Patient's question:
What problems may arise if the medication abortion is not clean?Do you need to consult a doctor to obtain the medication?
What precautions should be taken during medication abortion?
How many days does it take for medication abortion to be completed?
Doctor's answer:
Hello: The most important point first is that medication must be obtained from a regular hospital. After a detailed examination, the condition must be signed by family members, and then a professional doctor will prescribe and provide the medication.The mechanism of action for medication-induced abortion is as follows:
Mifepristone: Its main function is as an antiprogesterone.
(1) As a progesterone antagonist, it can replace natural progesterone in acting on the endometrium, occupying the progesterone receptors on endometrial cells.
(2) Its antiprogesterone effect leads to necrosis of the decidua, detachment and bleeding, dissolution of the corpus luteum, and stimulation of endogenous prostaglandin production.
(3) It acts on the hypothalamus and pituitary, inhibiting the secretion of gonadotropins, which also leads to corpus luteum dissolution.
(4) It promotes the degradation of cervical collagen fibers, softening the cervix.
(5) It enhances the sensitivity of uterine muscles to prostaglandins.
Prostaglandins: Commonly used include carboprost and misoprostol. Their mechanism of action is as follows:
(1) They cause contractions of the uterine smooth muscle.
(2) After uterine contractions, intrauterine pressure rises, leading to vasoconstriction of chorionic villi, local hypoxia, and necrosis and degeneration of the decidua, thereby disrupting the mechanisms that maintain early pregnancy.
(3) The synthesis of cervical collagen fibers is inhibited, making the cervix soft and easier to dilate.
(4) In animals, it has been observed to dissolve the corpus luteum.
When these two drugs are used in combination, they achieve anti-implantation, cervical softening, and uterine contractions to induce abortion, making medication-induced abortion a simple, safe, effective, low-side-effect, and low-pain method.
Indications
(1) Interruption of