Patient's question:
What is polycystic ovary syndrome? Can polycystic ovary syndrome be cured?Doctor's answer:
Hello, menstrual disorders, amenorrhea, anovulation, hirsutism, obesity, infertility combined with bilateral ovarian enlargement showing cystic changes are collectively referred to as Polycystic Ovary Syndrome (PCOS). Patients may exhibit all the typical symptoms mentioned above, or only some of them. However, infertility caused by ovulation disorders is the main clinical manifestation of PCOS.The exact cause of PCOS is not yet fully understood. Currently, it is believed that the excessive production of androgens by the ovaries is responsible, and this excessive production results from the synergistic effect of multiple endocrine system dysfunctions in the body.
The primary goal of PCOS treatment is to establish a normal ovulatory menstrual cycle, restore fertility, and eliminate hirsutism. Once a normal menstrual cycle is established, pregnancy becomes possible, the ovaries no longer produce excessive androgens, and hirsutism also disappears. The methods to restore a normal menstrual cycle are as follows.
(1) Clomiphene, also known as Clomiphene Citrate or Serophene. It is now widely recognized as the first-line treatment for PCOS. Clomiphene induces the hypothalamus to release gonadotropin-releasing hormone, which in turn stimulates the pituitary to release follicle-stimulating hormone (FSH), promoting the normal development of follicles. Elevated FSH levels are key to inducing ovulation in PCOS patients. Clomiphene treatment can induce ovulation in more than 80% of patients. The specific dosage is 50 mg once daily, starting from day 5 of the menstrual cycle, for 5 consecutive days. Ovulation typically occurs 7–10 days after treatment. If the treatment is ineffective after 1–2 cycles, the dose can be increased to 100 mg daily for 5 days. During treatment, basal body temperature should be measured...