Patient's question:
What is polycystic ovary syndrome? Can polycystic ovary syndrome be cured?Doctor's answer:
Hello, irregular menstruation, amenorrhea, anovulation, hirsutism, obesity, infertility combined with bilateral ovarian enlargement showing cystic changes are collectively referred to as Polycystic Ovary Syndrome (PCOS). Patients may exhibit all of the above typical symptoms or only some of them. However, infertility caused by ovulation disorders is the main clinical manifestation of PCOS.The exact etiology of PCOS is unclear. Currently, it is believed that the excessive production of androgens by the ovaries is the result of the synergistic effect of multiple endocrine system dysfunctions in the body.
The primary goal of PCOS treatment is to establish a normal ovulatory menstrual cycle, restore fertility, and eliminate hirsutism. Once a normal menstrual cycle is established, pregnancy can occur, the ovaries no longer produce excessive androgens, and hirsutism also disappears. The methods to restore a normal menstrual cycle are as follows.
(1) Clomiphene, also known as clomiphene citrate or clomiphene, is now widely recognized as the first-line treatment for PCOS. Clomiphene induces the release of gonadotropin-releasing hormone from the hypothalamus, which in turn promotes the release of follicle-stimulating hormone (FSH) from the pituitary gland, thereby promoting the normal development of follicles. Elevated FSH levels are key to inducing ovulation in PCOS patients. Clomiphene treatment can induce ovulation in more than 80% of patients. The specific dosage is 50 mg once daily, starting from day 5 of the menstrual cycle, for 5 consecutive days. Ovulation typically occurs 7–10 days after treatment. If treatment for 1–2 cycles is ineffective, the dose can be increased to 100 mg daily for 5 days. During treatment, basal body temperature should be measured...