Patient's question:
Problem Description: Hospital examination for leukoplakia of the vulva, heard that your hospital has medicine that can treat itDoctor's answer:
Vulvar leukoplakia is caused by epidermal thickening due to lesions, loss of pigment in the basal epidermal layer, and reduced blood vessels in the superficial dermis, leading to a decrease in color or white appearance of the vulvar skin or mucosa. Women diagnosed with "vulvar leukoplakia" often fear that it may be a precancerous lesion. In recent years, extensive clinical studies have confirmed that its canceration rate is only about 2%. In 1975, the International Vulvar Disease Research Society decided to abolish the term "vulvar leukoplakia" and refer to the condition as "vulvar leukoplakia" or "chronic vulvar dystrophy." Patients with white vulvar skin often remain unaware due to the lack of sensation, and the condition is usually discovered by a doctor. Some patients, however, may notice it during a visit for vulvar itching.Why does vulvar skin turn white? The exact cause remains unclear, but it is relatively well understood that when the vulvar skin is affected by certain diseases, the epidermis in the affected area becomes excessively keratinized, and the reduction in melanocytes leads to paler skin. The affected skin may thicken like leather, or it may become thin, dry, prone to cracking, and even develop ulcers or hard nodules. If vulvar skin turns white, whether or not itching is present, it is advisable to seek medical examination. Particular attention should be paid if the skin shows thickening, roughness, elevation, ulcers, or cracks, and surgical treatment may be necessary if needed.
Since "vulvar leukoplakia" is a persistent condition, long-term treatment and regular follow-ups are essential. Follow-up intervals of 3 to 6 months are recommended. With consistent treatment, generally satisfactory results can be achieved. Medications may include vitamin supplements. If vulvar itching is severe and affects sleep, mild sedatives may be prescribed. Locally, 1% hydrocortisone and 1–2% testosterone cream can be applied. This treatment