Can immune infertility be cured?

Patient's question:

Wanting a baby, but diagnosed with immunological infertility.

Doctor's answer:

Immune infertility can be treated, and the specific methods for treatment are as follows.
Recommendations:
1. Isolation Therapy: Women with sperm homologous immune infertility can use condoms for 3 to 6 months to avoid further stimulation of sperm antigens by the female. After the antibody titer decreases, sexual intercourse during the ovulation period can be attempted to achieve pregnancy.
2. Immunosuppressive Therapy: Corticosteroid drugs can be used to treat immune infertility. For example, prednisone 5mg can be taken three times daily for two weeks before ovulation. There are also reports of local vaginal application of hydrocortisone to treat infertile women with anti-sperm antibodies in cervical mucus. The reported pregnancy rate ranges from 20% to 45%.
3. Intrauterine Insemination: When sperm antibodies in cervical mucus interfere with conception, the husband's semen can be processed in vitro to isolate high-quality sperm for intrauterine insemination.

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