What is the reason for low non-invasive blood concentration?

Patient's question:

A few days ago, I went to the hospital for a non-invasive DNA test. The test results showed low blood concentration. I don't know what caused this situation—is it due to external factors or internal body issues? Will it affect the baby? What kind of help is needed: What are the reasons for low blood concentration in non-invasive tests?

Doctor's answer:

Some mothers, eager to know if their fetus has chromosomal abnormalities, even implement non-invasive DNA testing as early as 12 weeks or earlier. At this time, the amount of fetal free DNA in peripheral blood is too low, resulting in a concentration that is too low to be tested. This is the main reason. The mother being excessively overweight or underweight can also lead to low non-invasive DNA concentration. The collected blood has been exposed to prolonged handling during collection and transportation, partially degrading and causing the concentration to be too low.

📌 Related Posts