When should the Down syndrome screening be done?

Patient's question:

I got married last year. Recently, I've been experiencing lower abdominal pain, especially during my period. I'm very worried about it affecting my fertility, and I'm also extremely sensitive to cold and coldness. Could you please tell me at which week the Down syndrome screening should be done?

Doctor's answer:

The best time for Down syndrome screening is between weeks 15 and 20 of pregnancy. Down syndrome screening is a method that involves drawing blood from the pregnant woman to detect the levels of alpha-fetoprotein, human chorionic gonadotropin, and free estriol in the maternal serum. By combining this with the pregnant woman's due date, weight, age, and gestational age at the time of blood collection, it calculates the risk factor for giving birth to a fetus with congenital defects.

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