Patient's question:
Pregnant for 3 months, the first prenatal check-up involved a thorough examination of folic acid genes, which resulted in CT and AA genotypes. Is it necessary to continue taking folic acid until the baby is born, and is there anything else that needs to be digested?Doctor's answer:
It is recommended to enhance nutrition, prevent harmful contact, and maintain a positive mindset. During the fourth month of pregnancy, it is advisable to visit the hospital to schedule a prenatal screening for Down syndrome. The C677T mutation in the C677 gene can increase enzyme activity by 35% in the CT heterozygous type and by 70% in the TT homozygous type. The wild-type (CC) has normal folate catabolic function. Compared to the CC type of C677T, the CT type, TT type, and CT+TT type can increase the probability of folate catabolic dysfunction; compared to the AA type of A1298C, the AC type, CC type, and AC+CC type can also increase the probability of folate catabolic dysfunction. I hope this information is helpful to you. Wishing you good health!