Patient's question:
Why does the body lack progesterone? I would like to ask for advice.Doctor's answer:
Hello! Low progesterone is generally caused by luteal phase deficiency.The reasons for luteal phase deficiency include:
1. Insufficient FSH secretion during the follicular phase, with low levels of FSH and estradiol in the follicular fluid.
2. Inadequate LH peak during ovulation.
3. Insufficient LH secretion during the luteal phase or insufficient pulsatile secretion of LH.
4. Abnormal steroid hormone receptors in endometrial cells, leading to low responsiveness to hormones secreted by the corpus luteum. Even if the luteal function is normal, the endometrium may develop improperly.
Therefore, in such cases, it is generally necessary to supplement progesterone.