How to treat abnormal chromosomes in women

Patient's question:

I've been married for several years, and so far, we don't have any children. I'm very anxious about it and don't know if it's my problem. I've asked my husband to get checked, but he refuses. I'm very scared that my condition might worsen. How is it treated if a woman has abnormal chromosomes?

Doctor's answer:

According to your description, three or more consecutive natural miscarriages are considered habitual abortion, which is closely related to chromosomal abnormalities.
Recommendations:
1. Before pregnancy, it is recommended to undergo ovarian function tests, chromosomal tests for both partners, blood type identification, and semen analysis for the male partner. The female partner should also have a reproductive tract examination, including checking for tumors, intrauterine adhesions, and undergoing hysterosalpingography and hysteroscopy to determine if there are any uterine malformations or lesions, as well as cervical canal relaxation. If cervical canal relaxation is present, cervical canal repair surgery should be performed before pregnancy, followed by regular follow-up after the procedure.
2. For women with habitual abortion of unknown cause, when signs of pregnancy appear, treatment with progesterone for luteal phase deficiency can be administered, with a daily dose of 10–20 mg via intramuscular injection, or HCG 3000 U administered once every other day via intramuscular injection.
Lifestyle care:
1. If pregnancy is confirmed, continue medication until the 10th week of gestation or beyond the previous miscarriage month.
2. After pregnancy, rest in bed, avoid sexual activity, and supplement with vitamin E.
3. Maintain a positive mood and pay attention to nutrition.

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