Patient's question:
Can men also have immunological infertility? My wife has had three miscarriages.Doctor's answer:
Generally speaking, the male body produces an antigenic immune response to its own sperm. Although sperm have multiple antigens, their efficacy is low or changes, and their self-tolerance is compromised. In situations where an immune response should not occur, an immune response is triggered, leading to damage to sperm cells and ultimately resulting in male infertility. This is known as immunological self-reactivity of sperm.