Patient's question:
The mother of the girl's mother is the mother of the boy's father.That is to say, the mother of the girl and the father of the boy are first cousins.
What impact will the marriage between the girl and the boy have on future generations?
Doctor's answer:
You are both fifth-generation relatives. According to the law, you are allowed to marry. Marriage will have little impact on future generations. If both parties have common pathogenic genes, it may increase the risk of offspring developing recessive genetic diseases. During pregnancy, undergo comprehensive prenatal examinations. If any abnormalities are found, prenatal diagnosis should be performed. Couples who marry closely related may inherit the same gene from their common ancestors and pass it on to their children. If this gene follows an autosomal recessive inheritance pattern, the children may develop the disease because they are homozygous for the mutation. Therefore, close relative marriage increases the risk of certain autosomal recessive genetic diseases. In your case, it is outside the third generation, so you can marry.